Advancing the future of cancer therapy

Our clinical-stage pipeline comprises dual-cytokine immuno therapeutic candidates, built on our proprietary Navigated Delivery ™ FHAB platform to address significant unmet medical needs across oncology

Taking this navigated delivery platform into improving and enhancing the next generation of ADCs, an early stage candidate has successfully completed preclinical Proof of Concept and the platform is ready to deliver candidates for clinical trials and for partnering with other innovator ADC companies that want to improve their therapeutic efficacy and safety.

Pipeline overview

We have leveraged our proprietary FHAB technology platform into immunotherapy assets and ADCs for cancer treatment, demonstrating the ability and power of the Navigated Delivery™ platform to produce improved and advanced therapeutics.

Program

Indications

Stage

Program

GDT-001 (IL12-FHAB)

Soft-Tissue Sarcomas (STS),

solid tumors

Indications

Phase 1a

Stage

GDT-002 (IL12-FHAB-IL15)

Program

Solid tumors, bladder cancer

Indications

IND ready

Stage

GDT-003 (IL12-FHAB–IL-18)

Program

Solid tumors

Indications

Pre-clinical

Stage

GDT-101 (HER2+MMAE+Topo1)

Program

Solid tumors: Breast, lung

Indications

Pre-clinical

Stage

GDT-101 (HER2+MMAE+Topo1)

Program

Solid tumors: Breast, lung

Indications

Pre-clinical

Stage

Clinical Trials

For more information on our clinical trials, please visit the following pages (note these are historical trials carried out by Sonnet Biotherapeutics on the single cytokine IL12+FHAB)

SB101

GDT-001 Dose Escalation in Patients with Advanced Solid Tumors and Soft Tissue Sarcomas

SB102

Study of GDT-001 (IL12-FHAB) in Healthy Adults

Interested in Partnering or Collaborating?

Guidant Biotherapeutics is actively engaging with potential partners and licensees interested in leveraging the strength of our proprietary FHAB technology platform.

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